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BMS 539 Molecular Immunology (Laboratory–Lecture course)

Prerequisite: BMS 528. (Offered as needed/3 credits/lab fee)

This combined lecture and laboratory course is designed to introduce modern molecular concepts and techniques used in immunology. The lecture includes discussions of Ig gene assembly, rearrangements, regulation and expression; T-cell receptors; molecular mechanisms of antigen processing; and advances in antibody engineering. The laboratory exercises cover basic immunological techniques such as ELISA, immunoblot, hybridoma preparation aevaluation, immunoaffinity chromatography and phage display of antibody fragments.